(PDF/82.19 KB) Ask your pharmacist how to throw away medicines you no longer use. (PDF/84.29 KB) The United Kingdom (UK) withdrew from the European Union (EU) on 31 January 2020 and is no longer an EU Member State. The main measure of effectiveness was based on their blood uric acid levels.Adenuric was more effective than allopurinol and placebo in treating hyperuricaemia by reducing blood uric acid levels. These side effects were mostly mild or moderate in severity. (PDF/13.98 KB) For the full list of all side effects and restrictions with Adenuric, see the package leaflet.

(PDF/428.35 KB) See below for a comprehensive list of adverse effects. (PDF/105.06 KB) (PDF/523.69 KB) (PDF/490.68 KB)

Hyperuricaemia can lead to urate crystals forming and building up in the joints and the kidneys. (PDF/104.51 KB) Similar results were seen in the second study after a year.In patients with blood cancer who were undergoing chemotherapy, Adenuric was as effective as allopurinol in controlling blood levels of uric acid: in 98.3 % of patients (170 out of 173) on Adenuric blood levels of uric acid normalised compared with 96 % (166 out of 173) of patients on allopurinol.The most commonly reported side effects with Adenuric are gout flare-ups, abnormal liver test results, diarrhoea, nausea (feeling sick), headache, rash and oedema (swelling). When suggestions are available use up and down arrows to review and ENTER to select. (PDF/107.4 KB) (PDF/14.21 KB) Do not take a double dose to make up for a forgotten dose.Do not stop taking ADENURIC without the advice of your doctor even if you feel better. (PDF/100.04 KB) (PDF/106.51 KB) (PDF/446.23 KB) (PDF/456.77 KB)
These side effects were mostly mild or moderate in severity. On this page about Adenuric you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information.

It works by blocking an enzyme called xanthine oxidase, which is needed to make uric acid in the body. (PDF/746.52 KB) (PDF/25.44 KB) This was compared with 22% of the patients taking allopurinol (60 out of 268) and none of the 134 patients taking placebo. (PDF/730.52 KB) (PDF/13.79 KB) (PDF/620.9 KB) (PDF/48.24 KB) (PDF/102.4 KB) The first study, carried out in 1,072 patients, compared three doses of Adenuric (80, 120 and 240 mg once a day) with placebo (a dummy treatment) and allopurinol (another medicine used to treat hyperuricaemia). When this happens in the joints and causes pain, it is known as ‘gout’. It is not known if ADENURIC may pass into human breast milk. Rare serious hypersensitivity (allergic) reactions to Adenuric have occurred post-marketing.For the full list of all side effects and restrictions with Adenuric, see the package leaflet.The CHMP concluded that Adenuric was more effective than allopurinol at lowering blood uric acid levels including in patients undergoing chemotherapy , but that it could carry a greater risk of side effects affecting the heart and blood vessels.

Your doctor will have prescribed the strength most suitable for you.Continue to take ADENURIC every day even when you are not experiencing gout flare or attack.Start taking ADENURIC two days before chemotherapy and continue its use according to your doctor’s advice.
(PDF/13.82 KB)


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